Scientific journal
Научное обозрение. Медицинские науки
ISSN 2500-0780
ПИ №ФС77-57452

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RHEOLOGICAL CHARACTERISTICS OF ERYTHROCYTE IN HYPERTENSION WITH DYSLIPIDEMIA WITH ATORVASTATIN

Skorjatina I.A. 1
1 Kursk Institute of social education (branch of the institute RSSU (Russian State Social University))
The work purpose – to investigate possibilities of influence of an inhibitor gidroksi-metilglutaril coenzyme A-reductases - atorvastatin on microrheological properties erythrocyte at patients arterial hypertension with dyslipidemia. Under supervision were 33 sick АГ 1-2 degrees with dyslipidemia IIб type, risk 3 (criteria DAG 3 (2008), middle age (52,8±1,7 year). The control group was made by 26 healthy people of similar age. Results. Therapy atorvastatin patients arterial hypertension with dyslipidemia has appeared is capable to optimize quickly indicators lipid a spectrum of blood and a plasma FLOOR by 16 weeks of treatment, having provided changes lipid structure of membranes erythrocyte. As a result of treatment atorvastatin at patients the expressed easing activated intraerythrocytic the FLOOR at the expense of strengthening antioxidant protection erythrocyte is revealed. Application atorvastatin has caused in blood of patients maintenance increase diskozit, normalized already through 16 week treatments. Thus, the total quantity is reversible and is irreversible the changed forms erythrocyte decreased, stably having reached values of control to 16 week supervision. As a result of 4 months application atorvastatin sum normalization erythrocyte in the unit of their sizes and quantities is noted at increase freely lying erythrocyte.