Scientific journal
Научное обозрение. Медицинские науки
ISSN 2500-0780
ПИ №ФС77-57452

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FEATURES OF THE FORMATION OF MICROBIAL BIOFILMS ON VARIOUS SUBSTRATES. THE POSSIBILITY OF STUDYING BIOFILMS ON GALLSTONES

Vinnik Y.S. 1 Serova E.V. 1 Andreev R.I. 1 Peryanova O.V. 1 Rukosueva T.V. 1 Leyman A.V. 1 Michurov E.I. 1
1 SBEI HPE «Krasnoyarsk State Medical University them. prof. V. F. Voyno-Yasenetsky» of the Ministry of Health of the Russian Federation
To date, it is an accepted fact that the basic form of existence of bacteria in vivo are associated with the surface of the community – biofilms, which are highly organized, flexible, continuously changing heterogeneous community, consisting of both active functioning cells, because of the dormant forms enclosed in ekzopolimerny matrix, rather than individual planktonic cells. In the latest in domestic and foreign literature while a number of papers covering the microbiological aspect of the problems of gallstone disease, acute and chronic calculous cholecystitis, proving the important role of microorganisms in the development of diseases of the biliary tract and the formation of stones. However, the role of microorganisms in the biofilm development of acute and chronic inflammation, some strains of antibiotic resistance in the presence of stones in the gall bladder remains understudied.