Scientific journal
Научное обозрение. Медицинские науки
ISSN 2500-0780
ПИ №ФС77-57452

GENDER ASPECTS OF LABORATORY MONITORING INFESTATION OF TRICHIMONAS VAGINALIS

Gorchakov D.A. 1 Lutsevich I.N. 1
1 Saratov State Medical University n.a. V.I. Razumovsky
Identified gender specific immunological reactions, and changes in the oxidant/antioxidant system. In women with Trichomonas infections acute T-cell link of immunity is inefficient and humoral had a tendency to reduce. In men suffering from acute trichomonias, on the contrary, there was observed the activation of T-cell link, accompanied by an increase in IgM. Indicators of phagocytic activity of neutrophils in the blood of patients is higher than male patients. In chronic trichomoniasis in men noted depletion of T-cell immunity and increase of the production Ig G. Female patients was observed inhibition of T-cell factors and increased activity In-cell immunity. Indicators of phagocytic activity of women patients in the chronic form, were significantly lower than men’s. Antioxidant defense system were also identified gender-based features. Gender peculiarities of immunological reactions, and changes in the oxidant/antioxidant system largely affect the clinic трихомонадной invasion, formation of resistance Tr. vaginalis to medicines and should be considered when all methods of diagnostics and treatment of urogenital trichomoniasis.