Scientific journal
Научное обозрение. Медицинские науки
ISSN 2500-0780
ПИ №ФС77-57452

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EXPERIMENTAL ACTIVITY STIMULATION OF REGENERATIVE PERIODONTAL TISSUES KRAYNEVYSOKOY FREQUENCY ELECTROMAGNETIC RADIATION

Elizarov A.V. 1 Sirak S.V. 1 Kazieva I.E. 1 Bykov I.M. 2 Martirosan A.K. 1 Sirak A.G. 1
1 GBOU VPO “Stavropol State Medical University”
2 GBOU VPO “Kuban State Medical University”
The article discusses the results of the pilot study on the regenerative properties of the osteoplastic materials in combination with autologous fibroblasts and electromagnetic radiation, providing anti-edema effect, accelerating metabolic and repair processes in the tissues, which can serve as the basis for its application as a tool for the treatment of periodontitis. Anti-inflammatory activity of EHF EMR MM range studied in a model “felt granuloma” in 6 groups of animals. The experiment was conducted on 36 white mongrel male and female rats (12 for each group). The wound daily for 7 days exposed kraynevysokoy frequency electromagnetic radiation to millimeter wavelength of 7.1 mm for 45 minutes. In the control group in the postoperative period of this procedure was not performed. The study of reparative and metabolic processes in the newly formed connective tissue in the early postoperative period in all groups was performed according to cytomorphological parameters of red blood cells, blood collection needle puncture was performed in the surgical wound. The study shows that the developed method significantly stimulates the biosynthesis of glycosaminoglycans in chondrocytes. Metachromasia glycosaminoglycans increases substantially directly into the defect area, as well as areas adjacent thereto. It is established that a characteristic feature of the macromolecular architectonic wound defect under the influence of the proposed method is oriented arrangement of the macromolecules of collagen, which is of particular importance for the function restores tissue. Impact of the proposed use of a complex “osteoplastic material + autologous fibroblasts” on metabolic and repair processes in various structures of connective tissue origin has the same direction, which is confirmed by experimental data.