Scientific journal
Научное обозрение. Медицинские науки
ISSN 2500-0780
ПИ №ФС77-57452

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EXPERIMENTAL ASSESSMENT OF DENTAL IMPLANT MАTERIALY OSTEOGENIC POTENTIAL FOR BONE MARROW CELLS, CULTURED IN VITRO (FOR EXAMPLE POROUS TITANIUM)

Kazieva I.E. 1 Sirak S.V. 1 Zekeryaev R.S. 1 Sirak A.G. 1 Martirosyan A.K. 1
1 Stavropol State Medical University
The results of experiments carried out in vitro to study the effect of porous titanium on proliferation and differentiation of the osteogenic precursor cells determined from the medullary tissue. Found that the porous titanium bioinerten and can be successfully used to accelerate osseointegration in dental implantation. The results of these experiments in vitro, and preliminary in vivo studies in experimental and clinical on implantation of porous titanium granules in the artificially formed jaw defects suggest that the use of bio-inert material can be successfully used to accelerate the process of osseointegration in dental implantation. The study found that the test samples are biotolerable porous titanium metal, does not affect the proliferation and differentiation of osteogenic progenitor cells determined from bone marrow tissue. Installations preferential location fibroblast cells around the porous titanium granules from 5-th day from the beginning of the study.