Scientific journal
Научное обозрение. Медицинские науки
ISSN 2500-0780
ПИ №ФС77-57452

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FATAL CASES ANALYSIS OF PATIENTS WITH DESTRUCTIVE FORMS OF ACUTE PANCREATITIS

Kaliev A.A. 1
1 West Kazakhstan State Medical University named after M.Ospanov (Aktobe city
The thesis is based on posthoc analysis of 90 medical case histories of deceased patients with various forms of pancreatonecrosis for the period of 1997 to 2012 y. The main reasons of pancreatonecrosis that had resulted in fatality were abusive drinking behavior (37.8%) and pathobiology of biliary system (30.0%). Starting from 1997 to 2005 has been registered 83 cases of pancreatonecrosis (in this period died 33 – 39.7%) and from 2005 to 2012 the number of patients with pancreatonecrosis equaled to 168 (died 57 – 33.9%). 87 (96.6%) fall under surgical interference from 90 deceased patients. The first days from the moment of hospitalizing operated 54 (60%) patients and within 2-14 days – 33 (36.6%). At the first (pre-infected) phase of disease died 34 patients. At the second (infected) phase died 56 patients. From 2005 stick to noninvasive therapeutic approach. There were differences in the structure of fatality in the compared periods. If up to 2005 the prevailing part of fatal cases have been observed in the first phase of disease associated with haemodynamic damage and multiple organ failure then in the subsequent years due to the changes of therapeutic approach more often fatal cases observed at the late stages of pancreatonecrosis because of augmentation of endotoxemia and expansion of sepsis of abdominal origin.