Scientific journal
Научное обозрение. Медицинские науки
ISSN 2500-0780
ПИ №ФС77-57452

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FREE-RADICAL OXIDATION AND ANTIOXIDANT DEFENSE IN PERIODONTITIS

Karakov K.G. 1 Markarova G.V. 1 Elbekyan K.S. 1
1 Stavropol State Medical Academy
A synthetic analogue of pineal hormone melatonin, a medical product «Melaksen», has high safety, participates in restriction of stressful loadings and actions of Xenobiotics, is capable of inactivating the medicinal free radicals and raises the protective properties of the organism. In connection with this the use of pharmacological means possessing with antioxidant and membrane protective properties can be quite effective in the treatment of inflammatory diseases, including periodontal diseases. This paper examined the influence of Melaksen on lipid peroxidation and change of antioxidant activity in saliva of patients with chronic generalized parodonte of different severity level. On the basis of studies suppressing inflammatory processes in parodonte is established. The proposed scheme of treatment with use of electrophoretic injection in the form of a 1.5% aqueous solution creates conditions for obtaining express therapeutic effect.