Scientific journal
Научное обозрение. Медицинские науки
ISSN 2500-0780
ПИ №ФС77-57452

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STATE PORTAL BLOOD FLOW IN PATIENTS WITH NON-ALCOHOLIC FATTY LIVER DISEASE AND CARDIOVASCULAR DISEASE ACCOMPANYING

Krakhmalova E.O. 1 Kozlov A.P. 2
1 Institute of Therapy named after L. T. Maloy NAMS of Ukraine
2 Kharkiv National University named after V. N. Karazin
The article presents the results of research aim of which was studying the characteristics of portal, hepatic hemodynamic and structural changes in nonalcoholic fatty liver disease liver (NAFLD). It is shown that the combination NAFLD with hypertension or coronary heart disease leads to increased size of the liver, increase in hepatic and portal veins, changes of quantitative parameters that characterize the structure of the liver parenchyma, violation of hepatic and portal hemodynamics. Changes in portal hemodynamics and blood flow in these patients are characterized by a tendency to increase the diameter of the portal vein, reduced linear blood flow velocity in it, increased peripheral resistance index and represent a universal mechanism for remodeling of target organs liver and its vasculature.