Kurzanov A.N. 1
1 Kuban State Medical University
From the point of functional hystoarchitectonics, organs, being complex organized structures, consist of structural functional units - the smallest part of an organ that is able to fulfill its functions or one of its functions. A structural functional element is specific for each organ as a histophysiological microsystem, in which the character of interaction between cellular elements, microhemocirculation, ultra-circulation of tissue fluid, elements and components of interstitial space as well as regulatory effects, is relatively stable within the limits of this microsystem. The concept of space-time organization of structural functional units of organs has been added by our ideas about modular construction of structural functional units, which, from this point of view, are regarded as a combination of several modules. Module mutual coordination among the structural functional units is being achieved by means of local self-regulation of its functionally active elements and their interaction. Such regulatory effects can be provided by means of volumetric transmission of information in intercellular space with help of signal molecules, i.e. by mechanisms of volumetric bio-regulation. Volumetric regulation of the coordinated activity of all module components, forming the structural functional units, is aimed at achieving a total effective result of organ functioning.