Scientific journal
Научное обозрение. Медицинские науки
ISSN 2500-0780
ПИ №ФС77-57452

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SOME MECHANISMS OF PATHOGENESIS ANTIOXIDANTS IN THE TREATMENT OF TOXIC CARDIOMYOPATHY

Leshchankin N.Y. 1 Satybaldin O.A. 2 Tarasova T.V. 1 Yezhov O.A. 1 Vlasov N.A. 1 Chibisov S.M. 2 2
1 Ogarev Mordovia State University
2 Russian people friendship university
The big interest represents studying of an is functional-metabolic condition of uniform elements of blood at toxic conditions as they objectively enough reflect the general status of an organism and represent itself as the progressing mechanism endogenous intoxication. In the model of acute peritonitis found that the use of the drug with antioxidant activity etoksidola improves lipid cell membranes as cardiomyocytes, and red blood cells and platelets. Normalization of the lipid spectrum cytomembranes leads to improved functional status of red blood cells and platelets, which leads to improvement of the rheological properties of blood microcirculation processes, thus providing additional treatment options for toxic cardiomyopathy. The revealed essential updatings of a fatty metabolism in fabric structures of a myocardium at endogenous the intoxications connected with infringement of the basic electrophysiological functions of cages of heart, certainly, are one of the major pathogenetic factors of formation of toxic defeat of hear