Scientific journal
Научное обозрение. Медицинские науки
ISSN 2500-0780
ПИ №ФС77-57452

THE ROLE OF ACUPUNCTURE IN THE PROPHYLAXIS OF PLACENTAL FAILURE

Linde V.A. 1 Drukker N.A. 1 Romanova O.A. 1 Kravchenko N.A. 1 Ermolova N.V. 1
1 Federal State Government-Financed Organization “Rostov Research Institute of obstetrics and pediatrics” of the Ministry of Health of the Russian Federation
The role of intracellular regulatory polypeptides (activin-A, TNF-alpha, IL-1β, follistatin) in the development of placental failure in case of the menace of pregnancy terminationon the first trimester was detected. The abnormality of the existing metabolic correlation between the examined bioregulators that provide the trophoblast ivasion, was studied. The low level of Activin-A causes the decline of its inhibitory effect on TNF-alpha and IL-1β. The lowered content of Follistatin changes the function of Activin-A. The therapeutic effect of acupuncture in the prophylaxis of placental failure was studied. The therapeutic effect consists in the normalization of the content of endothelial factorof growth A (VEFG A) and in the normalization vasoactive components content in the blood serum, that is one of the principal indices of the placenta metabolicadequacy. The detected physiological level of endothelial factors after acupuncture is an indicator of haemodynamicsand oxygen balance improvement that is at the same time an objective criteria of the effectiveness of this method in prophylaxis of placental failure developing in the first trimester of pregnancy.