Scientific journal
Научное обозрение. Медицинские науки
ISSN 2500-0780
ПИ №ФС77-57452

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STUDY OF THE REACTION OF THE HYPOTHALAMIC-ADRENOCORTICAL SYSTEM TO STRESS AND STRESS CORRECTION VIOLATIONS ANTIOXIDANTS

Bolohova I.L. 1 Semenishcheva O.E. 2
1 Astrakhan State University
2 MBEH SHAM Lenina
The article is devoted to the influence of immobilization stress and action α-tocopherol on the functional state of neuroendocrine hypothalamus and adrenal glands. Based on a series of experiments on the 4 experimental groups showed that immobilization stress significantly decreased functional activity of supraoptic, paraventricular, suprachiasmatic and arcuate nucleus of the hypothalamus. Shown that the use of vitamin E significantly increase the peroxide resistance of erythrocytes, this fact shows antioxidant properties of α-tocopherol. Stress-effect of α-tocopherol on hypothalamic structure is most pronounced at the stage of age involution. Immobilization stress leads to changes in cell unidirectional fascicular zone of the adrenal cortex in different age periods of ontogeny.