Scientific journal
Научное обозрение. Медицинские науки
ISSN 2500-0780
ПИ №ФС77-57452

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RESORBABLE ENDOPROSTHESIS FOR ENDOBILIARY STENTING

MarkelovаN.M. 1
1 GBOU VPO Krasnoyarsk State Medical University. prof. VF Vojno-Yasenetsky Russian Ministry of Health
The paper presents the effectiveness of experimental models of stents made of polyhydroxyalkanoates for endobiliary prosthetics. Created at the Institute of Biophysics, Siberian Branch of the Russian Academy of Sciences (Krasnoyarsk) experimental base in biotechnology polyhydroxyalkanoate, the positive results of toxicological and biomedical research empowered the applicability of these polymers to construct biocompatible vascular stents. With the use of polyhydroxyalkanoates (PHAs) are developed and investigated self-expanding metal stents, modified polymer coating, including laden with cytotoxic drugs. In animal experiments, high efficiency coating of PGA to reduce reaction vessel wall and prevent complications that occur during the use of metal stents. Registered trademark of the material and plastic products – Bioplastotan.