Scientific journal
Научное обозрение. Медицинские науки
ISSN 2500-0780
ПИ №ФС77-57452

FEATURES OF CELLULAR AND HUMORAL IMMUNE SYSTEM IN PATIENTS WITH ALKOHOLIC CARDIOMYOPATHY

Martyanova O.I. 1 Bashta G.V. 1
1 Danylo Halytsky Lviv National Medical University
In this work we studied the factors that characterize the cellular and humoral immune system of patients with alcoholic cardiomyopathy (group number 1), coronary heart disease patients (group number 2) and healthy subjects (control group). As a result of the research in patients 1st and 2nd groups was observed a decrease in the population of T-lymphocytes (CD3+), indicating that the intensity of T-cell immunity with a tendency to the development of T-cell immunodeficiency due to a probable reduction parameters of T- lymphocytes (CD4+). Patients in group 1 also observed activation of humoral immunity by activating a subpopulation of B-lymphocytes (CD23 +) and an increasing number of average molecular circulating immune complexes. These changes form a violation of the humoral immune response and may directly affect the strengthening of the pathological process. As a result, complex study of killer mediated immunity is proved that patients of the 1st and 2nd groups characterized by increased killer activity immunity.