Scientific journal
Научное обозрение. Медицинские науки
ISSN 2500-0780
ПИ №ФС77-57452

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CLINICAL MANIFESTATIONS AND EFFECTIVE TREATMENT OF PATIENTS WITH RESPIRATORY SARCOIDOSIS, LIVING IN AREAS WITH VARIOUS ANTRHROPOGENIC LOAD

Bashaeva Z.R. 1 Mezhebovskiy V.R. 1
1 SPEI HPE «The Orenburg State Medical Academy” of the Ministry of Health of the Russian Federation
The analysis of the clinical course and efficacy of treatment of patients with sarcoidosis, living in areas different in degree of contamination of environmental protection was done. We took into account the nature of onset of the disease, the presence and severity of clinical manifestations, laboratory parameters (blood, urine and phlegm tests, blood chemistry, immune status), the results of instrumental studies (chest radiography , spirography, PBS), the therapy, the duration and effectiveness. Revealed that sarcoidosis of patients living in areas with high and low levels of contamination of the ecological environment, flows differently. In areas of high human pressure disease is characterized by a high frequency of common forms of latent flows, accompanied by weight loss, thoracalgia and obstructive disorders of ventilation. For patients living in areas with low human pressure, sarcoidosis most often occurs acutely, accompanied by extrathoracic manifestation , arthralgia and skin erythema. The effectiveness of treatment of sarcoidosis depends on the degree of environmental pollution of the territory of residence: in areas with high human pressure, the disease often takes a progressive and relapsing course, is accompanied by a higher rate of complications SCS therapy, compared with those living in areas with low human pressure, in which the most observed clinical cure.