Scientific journal
Научное обозрение. Медицинские науки
ISSN 2500-0780
ПИ №ФС77-57452

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EFFECT OF EXPERIMENTAL HYPERTHYROIDISM AND HYPOTHYROIDISM ON ELEMENTAL STATUS OF LABORATORY ANIMALS

Miroshnikov S.V. 1, 2 Notova S.V. 3 Timasheva A.B. 3, 2 Kvan O.V. 3
1 Orenburg State Medical Academy
2 Orenburg regional clinical hospital № 2
3 Orenburg State University
The paper presents the results of a study of the element status of laboratory rats with experimental hyperthyroidism and hypothyroidism. It was revealed that the state of the thyroid status affects mineral metabolism, with the greatest changes in the content of chemical elements are fixed in the body of rats with experimental hyperthyroidism. In both test groups revealed a significant (p <0.05) higher amounts, Co, V and Al. In this experimental animals with hyperthyroidism, compared with the control group revealed significantly higher values ​​Cr Cu, Fe, As, Mn, Ni, Zn and Cd. When comparing the experimental groups revealed that the body of animals found with hypothyroidism significantly lower content of Mg, P, Cr, Fe, I, Mn, Se, Si, Zn and higher - Sr. From the toxic elements in the body of rats with experimental hypothyroidism found significantly higher content of Al and Sr.