Scientific journal
Научное обозрение. Медицинские науки
ISSN 2500-0780
ПИ №ФС77-57452

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PHYSICO-CHEMICAL PROPERTIES OF RED BLOOD CELLS AT PATIENTS WITH DIFFERENT CLINICAL FORMS AND SEVERITY OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE

Muravlyova L.E. 1 Molotov-Luchanskiy V.B. 1 Klyuyev D.A. 1 Chaikovskaya N.A. 1 Kolesnikova E.A. 1
1 Karaganda State Medical University
The study of the osmotic resistance and sorption capacity of red blood cells at patients with chronic obstructive pulmonary disease (COPD) was done. There were 5 groups of patients. The 1 group (n = 27) included patients with COPD moderate severity, mixed clinical form (emphysematous and bronchial). The 2 group (n = 25) consisted of patients with COPD, severe, also mixed forms. Group 3 (n = 24) included COPD patients, moderate, bronchial form. Group 4 (n = 27) represented patients with COPD, severe, also bronchial form. Group 5 (n = 12) represented patients with very severe bronchial form of COPD. It was observed that the alterations of hypo-osmotic erythrograms at patients with COPD depended on clinical form and severity of the disease. At COPD patients an increase of the sorption capacity of erythrocytes and change in the coefficient Q, which characterize the binding of methylene blue with red blood cells and diffusion of the dye inside the cells were observed.