Scientific journal
Научное обозрение. Медицинские науки
ISSN 2500-0780
ПИ №ФС77-57452

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TIMES TO RELAPSES OF VULVA CANCER AND THEIR PROGNOSTIC FACTORS

Nerodo G. A. 1 Ivanova V. A. 1 Nerodo E. A. 1
1 Federal State Budget Institution «Rostov Research Oncologic Institute» Ministry of Health of Russia
We investigated 809 patients with vulva cancer retrospectively over the last 30 years. 203 patients (25.09%) had a relapse. The percentage of relapses for IV stage was 46.2, for III stage – 26.68 %, for I and II stages – 20.5 % and 18.2 % respectively. The stage of disease significantly influence the time to relapse: the higher the stage, the less the period of time to relapse is (form 59.3 to 7.24 months correspondingly). The time to relapse also depends on the depth of tumor invasion: the deeper tumor invasion, the shorter the period of time to relapse is. The relapses are observed more frequently during three years after end of treatment (73.19 %), that is why this period should be considered to be the most dangerous for relapses. During this period follow-up of vulva cancer patients should include both laboratory and instrumental methods of examination for early diagnosis of tumor relapse following by immediate treatment. The method of treatment also influence the time to relapse. The duration of period without relapse has considerably increased in III and IV stages patients treated with complex method including chemotherapy.