Scientific journal
Научное обозрение. Медицинские науки
ISSN 2500-0780
ПИ №ФС77-57452

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CLINICAL VALUE OF A BIOFILM AT PATIENTS WITH WIDESPREAD PERITONITIS

Plotkin L.L. 1 Parfyonov O.V. 1 Bordunovsky B.H. 1 Shapko I.P. 2
1 It is southern - the Ural state medical university
2 Kostonaysky regional hospital
Up to the present time the diffuse peritonitis remains one of the most frequent complications of the abdominal surgery. One of the problems, which arise in the course of treatment of peritonitis, is a problem of microbial resistance, which are the etiologic cause peritonitis, to the antimicrobial therapy. The article shows the relationship between the availability of a biofilm in patients with the diffuse peritonitis and the maintenance of the level of systemic inflammation, resulting reliable increase in the duration of fever , the long-term persistence of leukocytosis, the increase of the time of the complete rehabilitation of the abdominal cavity, the increase of 7-day case fatality rate. The use of clarithromycin in a complex of antimicrobial therapy leads to the destruction and disappearance of the biofilm.