Scientific journal
Научное обозрение. Медицинские науки
ISSN 2500-0780
ПИ №ФС77-57452

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THE GLUCOCORTICOID RECEPTION IN PATIENTS OPERATED FOR LUNG CANCER

Polyakov I.S. 1, 2 Bolshakov A.A. 3, 2
1 Regional Clinical Hospital № 1
2 АNO « Research medical center of Gerontology»
3 St. Petersburg Institute of Bioregulation and Gerontology
Damaging effect of stress hormones is determined not only by their high content in the blood, but also activity-limiting stress body systems. Stress-implement and stress-limiting mechanisms of the immune system are active receptors located on the surface membrane of lymphocytes, the glucocorticoid receptor type II (GKR II) implement the effect of stress hormones, and type III (GKR III) inhibit it. It is the balance of stress-implement and stress-limiting mechanisms defines the implementation effect of stress hormones in the body. In this aspect, the influence of the operating level of anesthetic and injury protection on the level of stress that particularly stress-limiting mechanisms play a major role in the incidence of postoperative complications. The article describes the results of the study stress that implement and stress constraints defined in surgical treatment of lung cancer. That is of great significance in surgical treatment of lung cancer.