Scientific journal
Научное обозрение. Медицинские науки
ISSN 2500-0780
ПИ №ФС77-57452

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CLINICAL EFFICACY CORONARY INTERVENTION FROM A PHARMACOLOGICAL MYOCARDIAL PROTECTION ADENOSINE IN CORONARY HEART DISEASE PATIENTS WITH LOW AND PRESERVED EJECTION FRACTION LEFT VENTRICULAR

Popovа M.A. 1 Maksimenko A.V. 2 Myronenko I.V. 3
1 Surgut State University
2 BU Khanty -Mansiysk District cardiology clinic Center for Diagnostics and Cardiovascular Surgery
3 MBUZ Polyclinic number 3
A prospective three-year observation of 172 patients with chronic coronary artery disease undergoing elective percutaneous coronary intervention (PCI) with stenting of the coronary arteries. The first group consisted of 42 patients with CHD ( LVEF ≤ 45%), which was held PCI without pharmacological myocardial protection by adenosine , the second group included 34 patients CHD with low LVEF that during PCI directly to the COP to pharmacological myocardial protection intracoronary administered adenosine - inducer of ischemic preconditioning , the third group consisted of 45 patients with preserved CHD (LVEF > 45%) left ventricular ejection fraction (PLVEF ) , which was conducted with the COP PCI without the use of adenosine , a fourth group consisted of patients CHD with PLVEF that during PCI to pharmacological myocardial protection intracoronary adenosine was administered (n = 51). It is shown that pharmacological myocardial protection by adenosine -induced ischemic preconditioning before the planned stenting of coronary arteries in patients with chronic coronary artery disease reduces the incidence of coronary intervention associated with myocardial infarction VIa with preserved LVEF from 13.3 % to 1.96 %, with a low LVEF , with 23 , 8% to 5.8 %, accompanied by a decrease reoperation revascularization within 12 months after PCI in patients with preserved LVEF from CHD 17.8% to 5.8 % in patients with low LVEF - fro CHD m 38.0 % to 14.7%.