Scientific journal
Научное обозрение. Медицинские науки
ISSN 2500-0780
ПИ №ФС77-57452

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THE STRUCTURAL ORGANIZATION OF GASTER IN METABOLIC ACIDOSIS

Bochkarnikova N.V. 1 Alfonsova E.V. 1
1 Zabaikalsky State University
The article containts data about infringement of structural organization of ingastermetabolic acidosis. Metabolic acidosis, caused in the experiment on 42 animals (cats) by intravenous injection 3 % a lactate acid in up to a pH level 7,2-6,5 and duration up to 15-180 min. According to the findings of electron microscopy during the first 15 - 30 minutes of acidosis at blood the pH 7,2 configuration of cellulated surface of endothelial cells of capillaries. In the cells of the stomach (main, parietalnae) similar changes occur in violation of the structure of the nucleus, mitochondria, endoplasmic reticulum and other.Significant changes are observed in the epithelial, parietal and main cells of the gastric glands. Occurs disintegration of the cytoplasm, violation of the structure of the nucleus, mitochondria, Vorsin secretory tubules, breaks cytoplasmic membranes of individual cells.At the pH 7,1 and the duration more 60 - 100 minutes uncovered changes inthe cells of the stomach should be interpreted as “irreversible”, “focal injuries”. The pH-displacement to 7,0 leads to the vacuolardegeneration and necrobiosis.