science-review.ru
Scientific journal
Научное обозрение. Медицинские науки
ISSN 2500-0780
ПИ №ФС77-57452
ISSN 2500-0780
ПИ №ФС77-57452
IMMUNOHISTOCHEMICAL CRITERIA OF DIAGNOSTICS OF SMALL PLAQUE PARAPSORIASIS, LARGE PLAQUE PARAPSORIASIS AND MYCOSIS FUNGOIDES
Sidikov A.A. 1
Zaslavsky D.V. 1
Zaitcev V.S. 1
Nasyrov R.A. 1
1 Saint-Petersburg State Peadiatric Medical University
208 KB
In work revealed results of the comparative analysis of data of clinical, histologic and immunohistochemical researches patients with small plaque parapsoriasis, large plaque parapsoriasis and mycosis fungoides. For the first time it is established that the increase in level of an expression of an antigene of the cutaneous lymphocytes associated antigen of Heca-452 (that according to certain authors is considered a sign of an early stage of mycosis fungoides) takes place also at small plaque parapsoriasis and large plaque parapsoriasis. The comparative analysis of an expression of markers macrophages CD68, T-lymphocytes CD3, cytotoxic T-lymphocytes CD8, an antigene of immature dendritic cells CD209/DC-Sign is carried out and at parapsoriasis and mycosis fungoides. For the first time the expression of an antigene of EBV is found in patients with small plaque parapsoriasis and large plaque parapsoriasis.