Scientific journal
Научное обозрение. Медицинские науки
ISSN 2500-0780
ПИ №ФС77-57452

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MPORTANCELEVEL CHANGESON THE BACKGROUNDOF MOLECULAR MARKERSPHARMACOLOGICAL CORRECTION IN PATIENTS AFTER EXTERNAL SHOK WAVE

Tarasenko A.I. 1 Glybochko P.V. 2 Svistunov A.A. 2 Tarasenko Yu.N. 1 Fedotov E.A. 3
1 Saratov State Medical University n. a. V. I. Razumovsky
2 First Moscow State Medical University n.a. I. M. Sechenova
3 GUZ «Saratov regional blood transfusion»
Cytokine imbalances emerging in patients with nefroltiazom during distance shock wave lithotripsy (SWL) requires finding new methods of pharmacological correction. Cytokine imbalances emerging in patients with nefroltiazom during distance shock wave lithotripsy (DUVLT) requires finding new methods of pharmacological correction. In modern conditions for effective evaluation of the treatment, use additional methods of diagnosis, both in domestic and foreign literature a lot of attention paid to the study of cytokines - biologically active compounds of protein nature, perform mediator function in the development of a number of pathological processes, including inflammation. Currently, diagnostic significance of cytokines is the statement of the fact of increase or decrease in their concentration in the patient with a specific disease. However, to assess the severity and prognosis of the disease, it is advisable to determine the concentration, as pro-inflammatory and anti-inflammatory cytokines in the dynamics. As a result of the dynamic screening of cytokine profile in patients with nephrolithiasis in the program DUVLT in urine proved the effectiveness of the proposed method we have a rational pharmacological protection of the renal parenchyma with the use of nimesulide, which is to normalize the cytokine imbalance against the damaging effects of the shock wave. As a result of the dynamic screening of cytokine profile in patients with nephrolithiasis in the program SWL in urine proved the effectiveness of the proposed method we have a rational pharmacological protection of the renal parenchyma with the use of nimesulide, which is to normalize the cytokine imbalance against the damaging effects of the shock wave.