Scientific journal
Научное обозрение. Медицинские науки
ISSN 2500-0780
ПИ №ФС77-57452

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IMPACT OF SOME DERIVATIVES OF TAURIN ON INDICES OF MYOCARDIAL ELECTRICAL INSTABILITY IN ANOLOG STUDY OF HYPERGLYCOSEMIA

Tuzhilkina S.V. 1 Usanova A.A. 1
1 Ogarev Mordovia State University
An investigation of some markers of myocardial electrical instability during the anolog study of hyperglycosemia was conducted. We studied the effects of derivatives of taurin on duration of the QT interval and heart rate variability. 3-hydroxypyridine succinate was used as a comparator agent. According to this investigation an increase of QT intervals duration and reduce of heart rate variability was founded. The use of comparator agent 3-hydroxypyridine succinate had no effect on the duration and estimates of QT intervals, but it allowed to increase heart rate variability by maintaining activity of the parasympathetic component of the autonomic regulation and restriction of sympathetic activation. The derivatives of taurin also allow us to limit the decline of heart rate variability. However, the use of new compounds allows to limit the growth activity of the sympathetic component of the autonomic regulation, it does not prevent the inhibition of parasympathetic activity.