Scientific journal
Научное обозрение. Медицинские науки
ISSN 2500-0780
ПИ №ФС77-57452

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EVALUTION OF EFFICIENCY OF COMPLEX TREATMENT OF PATIENTS WITH GENERALIZED PERIODONTITIS WITH APPLICATION OF IMMUNOHISTOCHEMICAL METHODS

Bulkina N.V. 1 Golomazova E.A. 1 Tokmakova E.V. 1
1 Saratov State Medical University n.a.V.I. Razumovsky
Aggressive form of periodontitis is now becoming more common. Due to the low efficiency of antibacterial therapy in recent years, increasing use is being made non-medicine therapy. Since to date no data on the pathogenic effects of electromagnetic radiation on the diffuse the endocrine system the oral cavity of patients fastprogressive periodontitis, so the purpose of the study was to increase the effectiveness of treatment of patients with fastprogressive periodontitis (FPP) by incorporating complex combination of EHF-therapy laser therapy apparatus «Matrix» using specialized dental tips LO-EHF-4, 9 (λ = 4,9 mm). Evaluation of the results was carried out on the basis of immunohistochemical and morphometric analysis of the functional morphology of mast cells gums that contain serotonin and histamine. The study found a direct correlation between the amount of morphometric parameters of mast cells that produce serotonin and histamine, and the degree of periodontal inflammation. Therefore, the diffuse neuroendocrine together with microbial and immune factors play a major role in the pathogenesis of recurrent FPP and EHF laser can improve the condition of its components and, ultimately, to achieve a more sustainable stabilization of inflammatory and destructive processes in periodontal tissues.