Scientific journal
Научное обозрение. Медицинские науки
ISSN 2500-0780
ПИ №ФС77-57452

Personal portfolio

THE INFLUENCE OF EXPERIMENTAL LACTATE-ACIDOSIS ON THE STRUCTURAL ORGANIZATION OF THE PANCREAS

Alfonsova E.V. 1
1 Zabaikalsky State University
The article describes results of structural organization of pancreas in the process of experimental lactic acidosis. A number of runs were held in which acidosis of different depth from 7.2 blood pH till 6.5 blood pH and duration from 30 and 180 minutes was created. Vascular congestion, oedema of vessel wall and circumvascular spatium, blood congestion of different varying post-meal symptom severity, microthrombosis and microhemorrhages in parenchymatous tissue of pancreas occur as a result of blood shearing till 7.2 pH. When blood pH is 7.1 or lower endothelial tissue desquamation, structural damage of endotheliocytes, subendothelium exposure, oedema of parenchymatous tissue, connective-tissue matrix in vessels of microvasculature are defined. And one can observe destruction of organ agyrophilic scaffold, necrobiosis and necrosis of microcell elements.