Scientific journal
Научное обозрение. Медицинские науки
ISSN 2500-0780
ПИ №ФС77-57452

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MODERN CONCEPTS ABOUT PROBLEM HEMATOLOGICAL COMPLICATIONS COMBINED ANTIVIRAL THERAPY FOR CHRONIC HEPATITIS C

Ambalov Y.M. 1 Dontsov D.V. 1 Mamedova N.I. 1
1 Rostov State Medical University
Use in patients with chronic hepatitis C combination antiviral therapy with interferon and ribavirin achieves in most cases, sustained virologic response, which indicates a positive treatment outcome. However, in some patients during treatment with the development of various side effects. A special place among the adverse events of specific therapy for chronic hepatitis C take haematological disorders. The sharp decline in the number of peripheral blood erythrocytes, neutrophils and platelets often requires a dose reduction of antiviral drugs or complete cessation of the therapy. In this review article we have tried to present the existing scientific literature on the clinical manifestations, pathogenesis and methods of the features of a possible correction of hematological complications of combination antiviral therapy for chronic hepatitis C.