Scientific journal
Научное обозрение. Медицинские науки
ISSN 2500-0780
ПИ №ФС77-57452

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FEATURES OF LIPID PEROXIDATION DURING POSTIMPLANTATION PURULENT COMPLICATIONS AND THEIR CORRECTION

Andrievskih I.A. 1 Potemkin A.V. 1 Sinitskiy A.I. 1
1 South Ural State Medical University
Postimplantation septic complications are severe surgical infection, characterized by a long passage, multistage surgical treatment is often accompanied by removal of the implant, the patient’s disability. Development of implant infection accompanied by exudative-destructive inflammation, one component of which is the process of lipid peroxidation. Intensity of oxidative stress largely determines the severity of the disease and affects the outcome of inflammatory genesis. nalyzes the results of treatment of 125 patients with purulent complications after implantation. According to the study, it was found that the development of acute purulent inflammation is accompanied by activation of free radical oxidation and the accumulation of lipid peroxidation products in the blood. Activation of free radical oxidation may be the cause of prolonged exudative-destructive inflammation in the development of post-implantation of suppurative complications and cause poor outcomes. Additional correction adaptive responses to this serious category of patients contributes to more effective treatment of post-implantation complications.