Scientific journal
Научное обозрение. Медицинские науки
ISSN 2500-0780
ПИ №ФС77-57452

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THE PATHOMORPHOLOGICAL CHANGES IN THE LIVER OF PATIENTS WHO DEAD FROM HIV/TB CO-INFECTION

Bykhalov L.S. 1
1 Volgograd state medical University
The pathological characterization of specific and nonspecific changes in the liver of patients with tuberculosis in HIV infection was given. Morphologically identified specific tuberculous changes in 30% of cases, which was characterized by miliary dissimination in the capsule and / or in the parenchyma as millet diffuse tubercles, detect multiple epithelioid cell granulomas formed without caseous necrosis with macrophage component, involving giant cells Pirogov-Langhans. Various types of degenerative changes of hepatocytes was detected in 100% of cases, not rarely had a mixed character, combined with focal necrotic changes with different severity of fibrosis of the portal tracts in 38%, and there has been the development of productive vasculitis, microabscesses in the liver in 16% of cases.