Scientific journal
Научное обозрение. Медицинские науки
ISSN 2500-0780
ПИ №ФС77-57452

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THYROID STATUS AND DYNAMICS OF ANTITELOGENESIS TO THYROID HORMONES DEPENDING ON THERAPEUTIC MEASURES IN PATIENTS WITH SYSTEMIC LUPUS ERYTHEMATOSUS

Gontar I.P. 1 Paramonova O.V. 2 Rusanova O.A. 1 Maslakova L.A. 1 Zborovskaya I.A. 1 Emelyanov N.I. 2
1 Scientific-Research Institute of Clinical and Experimental Rheumatology
2 Volgograd State Medical University
The Purpose of this study was to analyze clinical and laboratory manifestations of SLE in accordance with the presence or absence of an increased number of antibodies to thyroid hormones to thyroxine (T4) and triiodothyronine (T3). Revealed that the most frequent clinical manifestations were: skin lesion 28 (75.7 percent), joint - 33 (89,1%), cardiovascular system - 34 (91,9%), nervous system - 12 (32.4%), eye -11 (29,7%). The presence of vasculitis and polyserositis was noted in 11 people (29,7%), anemia - 10 (27,0%), and leukopenia u(32,4%), Raynaud’s syndrome - in 16(43.2 per cent). Antinuclear factor was detected in 19(51,3%), antibodies to nDnc - 37(89,1%) patients. However, a statistically significant difference from negative for antibodies by the group of SLE patients (p<0.05) was observed only in the presence of skin lesions, blood vessels, joints and cardiovascular system.