Scientific journal
Научное обозрение. Медицинские науки
ISSN 2500-0780
ПИ №ФС77-57452

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ANTIBIOTIC RESISTANCE OF PERIIMPLANT INFECTION AGENTS

Gordinskaya N.A. 1 Mitrofanov V.N. 1 Komarov R.N. 1 Sabirova E.V. 1 Abramova N.V. 1
1 Federal State Budgetary Institution «Privolzhsky Federal Research Medical Centre» of the Ministry of Health of the Russian Federation
The analysis of periimplant infection agents showed a leading etiological role of staphylococci, accounting for 2/3 of all isolated microflora. Molecular genetic research revealed the presence of mecA gene in every third staphylococcus. The phenotype of methicillin-resistant staphylococci was found both in aureus and coagulase-negative strains. Among the Gram-negative bacteria the fermenting (Klebsiella oxitoca, Enterobacter cloacae) and non-fermentative bacillus (Pseudomonas aeruginosa, Acinetobacter baumanii) were separated (isolated). Two isolated enterobacteria strains produced extended-spectrum β-lactamases and were susceptible to carbapenems only. Acinetobacters (two strains of Acinetobacter baumanii in three isolated strains) were carriers of ОХА-40-like carbapenemase gene. Pseudomonas were sensitive to aminoglycosides, cephalosporins and carbapenems. Enterococci (3 strains) were susceptible to all antimicrobial drugs.