Scientific journal
Научное обозрение. Медицинские науки
ISSN 2500-0780
ПИ №ФС77-57452

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CHANGE OF BIOCHEMICAL INDICATORS IN ORAL LIQUID IN SECONDARY EDENTULOUS WITH CHRONIC GENERALIZED PERIODONTITIS

Gorkunova A.R. 1
1 Kuban State Medical University Krasnodar
The studies found that chronic generalized periodontitis are expressed disturbances in biochemical indicators of oral fluid, primarily reflecting the work of nonspecific protection: lysozyme, ceruloplasmin. Content of lysozyme in saliva of patients with chronic generalized periodontitis background edentulous differences extent accompanied by a significant reduction (average 33.2%), due to lower content of which is marked increase in the concentration of ceruloplasmin by 58.1%, which was of a compensatory nature and associated with increased redox processes in the oral cavity due to ceruloplasmin than objectively reflects the state of metabolic processes in the oral cavity. In chronic generalized periodontitis in oral fluid revealed a decrease of protein concentration and pH shift to the acid side. Application of prosthetic designs on this background accompanied by inhibition rate of salivation, increased shear response of the medium to the acid side, reducing its content of protein due to inhibition of secretory function. Was most pronounced adverse effects of prostheses using acrylic plastics, their use significantly reduced the rate of salivation by 24.4%, 9.5% had been a shift in the pH of the acidic side.