Scientific journal
Научное обозрение. Медицинские науки
ISSN 2500-0780
ПИ №ФС77-57452

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MORPHOMETRY OPTIONS AND THE IMMUNOHISTOCHEMICAL MARKERS OF FIBROSIS AND INFLAMMATION IN THE EARS ATRIUMS IN PATIENTS WITH ATRIAL FIBRILLATION OF DIFFERENT ETIOLOGY

Grigoriadi N.E. 1, Vasilez L.M. 2, Tuev A.V. 2, Kosareva P.V. 2, Latysheva S.Y. 3, Gordiichuk R.N. 4, Scherbenev V.M. 4
1 Permskaya Regional Clinical Hospital
2 Perm State Medical Academy. ak. EA Wagner
3 Regional Hospital RZD
4 Permskaya Regional Clinical Hospital № 2 «Heart Institute»
Studied the morphometric characteristics and severity of tissue expression of markers of fibrosis and inflammation in atrial myocardium by immunohistochemistry in patients with different forms of atrial fibrillation , including arterial hypertension and coronary heart disease progression . The main group included biopsies of the atrial appendages of 55 patients with atrial fibrillation of different etiologies. Atrial endocardial fibrosis ears begin to form , smiling in patients with idiopathic atrial fibrillation , progressing in patients with arterial hypertension and atrial fibrillation , and reach a maximum in the group with coronary artery disease , hypertension and AF. In the tissues of the atrial appendages revealed increased expression of immunohistochemical markers of inflammation and fibrosis . Expression of matrix metaloproteninazy -9 and tumor necrosis factor -α progressively in-creases in patients with hypertension and its combination with coronary artery disease .

Библиографическая ссылка

Григориади Н.Е., Василец Л.М., Туев А.В., Косарева П.В., Латышева С.Э., Гордийчук Р.Н., Щербенев В.М. ОСОБЕННОСТИ МОФРОМЕТРИЧЕСКИХ ПОКАЗАТЕЛЕЙ И ИММУНОГИСТОХИМИЧЕСКИХ ПАРАМЕТРОВ ФИБРОЗА И ВОСПАЛЕНИЯ В УШКАХ ПРЕДСЕРДИЙ У ПАЦИЕНТОВ С ФИБРИЛЛЯЦИЕЙ ПРЕДСЕРДИЙ РАЗЛИЧНОЙ ЭТИОЛОГИИ // Научное обозрение. Медицинские науки. 2015. № 1. С. 138-139;
URL: https://science-medicine.ru/en/article/view?id=739 (дата обращения: 21.07.2026).