Scientific journal
Научное обозрение. Медицинские науки
ISSN 2500-0780
ПИ №ФС77-57452

Personal portfolio

SEASONAL DYNAMICS OF HEMOSTASIS AND MICROCIRCULATION INDICES WHILE EXPERIMENTAL BURN TRAUMA AND AGAINST THE BACKGROUND OF CORRECTION BY COMPLEX PHYTOADAPTOGENS

Datieva F.S. 1, 2 Khetagurova L.G. 2 Urumova L.T. 1, 2
1 North Ossetian State Medical University
2 Institute of Biomedical Research VSC RAS and RNO-Alania
The analysis of indicators of blood coagulation and microcirculation indices was performed in healthy animals, in two groups of intact rats taken complex phytoadaptogens (phytococktails «Biorhythm-E» and «Biorhythm-RG»), and in 3 groups of rats with the experimental burn trauma, on the 1, 7 and 21 days after the burn in winter and summer seasons. The impairments in the hemostasis were characterized by the hypercoagulative syndrome development with the chronic DVS-syndrome effects in experimental rats. The phytococktails’use had the expressed hypocoagulating effect in intact animals, more expressed in winter. Reception of phytococktails while burn trauma reduced extent of hypercoagulation and microcirculation impairments, also more effective in winter. Complex phytoadaptogen «Biorhythm-RG», containing Rhodiola rosea and a Inula, was more effective during both seasons. Correlation analysis showed, that complex phytoadaptogens take part in the harmonization of interrelations between hemostasis links and microcirculation, improve the microcirculation («Biorhythm-E») and may be recommended as prophylactic means, as well as in complex rehabilitation while burn trauma.