Scientific journal
Научное обозрение. Медицинские науки
ISSN 2500-0780
ПИ №ФС77-57452

Personal portfolio

COMPARATIVE STUDY OF STRESS-PROTECTIVE EFFECT OF CYTOFLAVIN AND CARDIOXIPIN ON SAMPLE EXPERIMENTAL LIPID METABOLISM DISORDERS

Vodopjanova O.A. 1 Khoroneko S.E. 2 Antropova N.V. 1 Rodina O.P. 1 Moiseeva I.Y. 1
1 Penza State University
2 Ogarev Mordovia State University
The research has been conducted on the of drugs with antioxidant activity cytoflavin and cardioxipin on the behavior of male rats of white rats with experimental lipid metabolism disorders. Experimental lipid metabolism disorders was modeled during ten days by exogenous cholesterol in a dose of 40 mg per kg and vitamin D2. The animals were divided into the following four groups: intact, experimental lipid metabolism disorders (controlled), experimental lipid metabolism disorders with cytoflavin correction, and experimental lipid metabolism disorders with cardioxipin correction. Drugs were administered for ten days. Psycho-emotional state of the animals was assessed by studying the behavior of the test “open field”. The experimental work showed that under the influence experimental lipid metabolism disorders of cytoflavin and cardioxipin showed the anxiolytic effect. The cytoflavin anxiolytic activity was more sufficient.