Demidova L.A. 1
Panova T.N. 1
Demidov A.A. 1
1 Astrakhan State Medical Academy
To establish the ability to forecast the outcome of neurocirculatory dystonia (NCD) in hypertensive disease (HD) at patients with undifferentiated connective tissue dysplasia (NDCT) a retrospective analysis of medical documentation of 1632 patients with major cardiovascular diseases: NCD, HD, ischemic heart disease in the period from 2002 to 2012 was conducted. Then were selected 322 patients with a diagnosis of NDC currently or in history, which were divided in 2 groups: patients with NCD on the time of the study - 96 and patients HD - 226. The main clinical manifestations and experience of NDC at the time of the study were analyzed and then the patients with signs NDCT were selected to examined for the presence of autoantibodies (AAB) to collagen II and III types. The Associations between the main syndromes NCD, phenotypic characteristics of NDST with the presence of antibodies to collagen II and III types of the examined patients were studied. The correlation between the number of syndromes NCD and NDCT, the presence of AAT to collagen II and III types and their activity and subsequent development GB was established.