Scientific journal
Научное обозрение. Медицинские науки
ISSN 2500-0780
ПИ №ФС77-57452

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ASSOCIATION OF POLYMORPHISM OF LIMPHOTOXIN Α (+250 A/G LTΑ) WITH FORMATION OF CHRONIC TRUE ECZEMA

Denisova Y.E. 1 Churnosov M.I. 1
1 Federal State Autonomous Educational Institution of Higher Professional Education «Belgorod State National Research University» (“BelSU”)
In article the association of polymorphism of +250 A/G Ltα with formation of chronic true eczema is studied. Features of association of a studied candidate gene with eczema emergence depending on a floor are revealed. Based on these data we can conclude that the allele +250 G Lt α plays an important role in the formation of chronic eczema and is a true risk factor for developing the disease (OR = 1,33). The findings lead to the following conclusions: first, genetic polymorphism +250 A / G Ltα involved in the formation of the true exposure to chronic eczema in the population of the Central Chernozem Russia, and secondly, the peculiarities of the association studied candidate gene with the emergence of hand eczema depending on gender.