Scientific journal
Научное обозрение. Медицинские науки
ISSN 2500-0780
ПИ №ФС77-57452

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ASSESSMENT OF LEFT VENTRICULAR (LV) DIASTOLIC FUNCTION INDICES AND LEFT ATRIAL (LA) SIZE AGAINST LV GEOMETRY PATTERNS IN WOMEN WITH ARTERIAL HYPERTENSION (HT) ASSOCIATED WITH DIABETES MELLITUS TYPE II (DM) AND ISOLATED HT

Ivanova T.V. 1 Kinzerskaya M.L. 1 Korolev S.V. 1
1 State health care institution «Chelyabinsk Regional Cardiology Dispensary»
Comparative assessment of left ventricular diastolic function (LVDF) indices against various types of LV geometry has been carried out in women with arterial hypertension (HT) associated with diabetes mellitus type II (DM) and isolated HT with evaluation of their relation to left atrium (LA) size. Standard echocardiographic examination and pulsed-wave tissue Doppler echocardiography in probands has been done using ultrasonic scanner «Philips HD 11-XE». All probands have been divided into groups according to LV geometric pattern, LV myocardial mass index and relative mural thickness (RMT). Evaluation has been given to indices of left ventricular diastolic function such as: maximum velocity of early (e’max) and late (a’max) diastolic filling, E/A ratio, isovolumic relaxation time (IVRT), left ventricular end-diastolic pressure (LVEDP), time for early filling deceleration of left ventricle (dtE) and LA size (area and vertical dimension). It has been determined that left ventricular function disorder is more expressed in patients with HT associated with DM and that the degree of changes in diastolic function both in patients with isolated HT and HT associated with DM does not depend on changes in type of LV geometry. Left atrial size in patients with isolated HT and HT associated with DM is greater as compared to probands within control group. Left atrial area has a positive correlation with HT experience both in women with DM +HT and isolated HT when the left atrial longitudinal size correlates with DM experience. No changes in left ventricular end- diastolic pressure and left atrial pressure have been detected in patients with HT and HT associated with DM. No clear dependence on changes in LV geometric has been observed.